The Twenty One hotel is located in the city centre of Rome, near the city's most famous places of interest, including the Vatican and Saint Peter's Basilica, Piazza del Popolo, the Spanish Steps, the Pincian Hill and Villa Borghese.
23 via cola di rienzo, Rome, Italy - Vatican city
Amenities
Wellness facilities
Heated swimming pool
Sauna
Solarium
Fitness centre
Beauty salon
Non-smoking rooms
Entertainment & Leisure
Outdoor swimming pool
In-house entertainment
Nightclub/DJ
House Rules
Pets not allowed
General services
Wi-Fi
Babysitting
Multilingual staff
VIP Facilities
Daily newspaper
Doctor on call
General amenities
Gift Shop
Air conditioning
Designated smoking area
Disabled access
Elevator
Safety deposit box
Shops in hotel
Terrace
Parking Facilities
Private parking
Dining
Restaurant
Breakfast
Buffet breakfast
Bar
Room service
Room services & amenities
Family rooms
Reception services
24-hour front desk
Reception
Concierge
Currency exchange
ATM/cash machine on site
Luggage storage
Ticket counter
Tour organisation
Tourist information
Cleaning Services
Dry cleaning
Laundry facilities
Ironing service
Transport Services
Airport transfer
Car hire
Shuttle service
Business facilities
Business centre
Fax machine
Fax/photocopying
Meeting/Banquet Facilities
Photocopy machine
Conditions
Check-in/ Check-out
Check-in 02:00 PMCheck-out 11:00 AM
Credit cards accepted by the hotel
Visa, MasterCard, American Express, Maestro
About this property
Location
Italy>Rome>Vatican city
Number of rooms
86
Hotel TwentyOne
Reviews
Tripadvisor Reviews (2029)
4 /5This average is based on 2029 reviews
Cleanliness
Sleep quality
Value
Service
Location
L
laureneve19Manchester, Greater Manchester, England June 2026
Don’t book
Misleading Room Description
We booked a deluxe room specifically because the hotel's website advertised a balcony with "stunning views" and showed images of glass-fronted balconies overlooking the ci...
show more
S
SuttonJewellBirmingham, West Midlands, England May 2026
Good location, Tiny Bathroom, No Storage
Double room: The hotel was clean and the beds were comfortable although the room was not huge. Bathroom was minuscule with nowhere to put toiletry bags or other items. No storage in room, no drawers...
show more
S
S5323IMgbApril 2026
Great location, but disappointing bedroom
The hotel is ideally situated if you want to walk to the Vatican and old Rome.
Our bedroom (121) benefitted from a large balcony overlooking the main road, but was very small and dark with extremely ...
Don’t book
Misleading Room Description We booked a deluxe room specifically because the hotel's website advertised a balcony with "stunning views" and showed images of glass-fronted balconies overlooking the ci...
show more