Hotel San Isidro is located in São Gabriel, a city in the western region of Rio Grande do Sul, Brazil. The hotel sits along the BR-290 highway, offering easy access to the city's urban center about 2 km away. Nearby attractions include the São Gabriel Historical Museum and the Praça Getúlio Vargas square, both within 5 km. The closest major airport is Santa Maria Airport, approximately 93 km from the hotel.